Monocyte-dependent regulation of T lymphocyte activation through CD98
نویسندگان
چکیده
منابع مشابه
Lymphocyte activation: T-cell regulation by CTLA-4
The initiation of immune responses usually requires interactions of T lymphocytes with antigen-presenting cells. The specificity of these interactions depends on the recognition by the T cell’s antigen receptor of an antigenic peptide presented in a complex with molecules of the major histocompatibility complex (MHC). But a successful immune response requires additional costimulation of the T c...
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Immunological patrolling of the central nervous system (CNS) The normal CNS is often referred to as an immunologically privileged site. Two of the more important factors contributing to this are as follows. First, the CNS is, in most places, 'encapsulated' within the blood-brain barrier (BBB) formed by specialized endothelium whose basement membrane is in contact with glial cells of this tissue...
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Background: MicroRNA-155 (miR-155) is upregulated during T cell activation, but the exact mechanisms by which it influences CD4+ T cell activation remain unclear. Objective: To examine whether the B and T lymphocyte attenuator (BTLA) is a target of miR-155 during naïve CD4+ T cell activation. Methods: Firefly luciferase reporter plasmids pEZX-MT01-wild-type-BTLA and pEZX-MT01-mutant-BTLA were ...
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We previously reported that with time, after antigenic stimulation of antigen-regulated murine T lymphocyte clones, total IL-2-R expression decayed 10-50-fold, commensurate with a decline in the ability of the cells to proliferate to IL-2. However, late after antigenic stimulation, when the cells were refractory to the IL-2-proliferative stimulus, high levels of high affinity IL-2-R remained. I...
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ژورنال
عنوان ژورنال: International Immunology
سال: 1997
ISSN: 1460-2377
DOI: 10.1093/intimm/9.9.1221